Now you see why I asked for an accurate schematic, photos and layout, as without that info, no one else can have a clue whether the problem is due to the design, its implementation, or a bad component.
Twisting wires may be beneficial in the case of a pair of wires carrying balanced signals, or when one or more of the wires has a low impedance connection to 0V common.
Also it may help in the case of wires carrying signals of opposing polarity with some gain between them, eg grid and anode of the same stage, anode and anode of cascading stages. Because capacitance between the wires will create a negative feedback loop, rolling off high frequencies, thereby improving stability.
Good info, thanks!