I haven't had it too long so I haven't spent much time running it with my VM set to high gain. I used it with some slight crunch in low dynamic mode but mostly was using it with my old Vibro Champ and a Silvertone 1482. It's a really cool pedal and it does clean up pretty well when you roll down your guitar's volume control. It's got a ton of adjustability as far as clarity and tone go so you can dial in just about any fuzz tone you want and it really works well with other pedals. I like stack mine for a Gilmour lead tone with a clean boost or OD in front (which depends on the amp I'm using) then I run it through a M108 to set the tone exactly the way I want it then into a chorus with it's speed set on zero and then to my delay. It nails that Comfortably Numb tone.
Here is how I have it layed out on my board with my 1482:
With my Champ I swap the SD1 with a Route 66.
It's got an amazing amount of range and can go from Big Muff to distortion pedal which is really cool. It's got it's own LPB-1 circuit built in too and sometimes for a more distortion pedal sound I'll run a SD1 or Route 66 in front of it, adjust the fuzz to zero on the Musket and max it's boost control. It gets the coolest blues tone with my Lester set to it's neck pup and it's volume rolled back to around 4 or 5. It's the swiss army knife of fuzz boxes, that's for sure.
